- authorisedPhase I and Phase II (Integrated)- First administration to humans
A Phase I/II, randomized, placebo-controlled, multi-arm, dose-finding study to evaluate the safety, efficacy and immunogenicity of an Acne mRNA vaccine candidate in adults with moderate to severe acne 18 to 45 years of age
This clinical trial is testing a new mRNA vaccine for adults aged 18 to 45 with moderate to severe acne. Researchers want to find out if the vaccine is safe, how the immune system responds to it, and whether it helps reduce spots on the face.
Spain · Germany · Poland - recruitingPhase IV
Low-dose isotretinoin versus standard-dose isotretinoin to treat severe acne in young people – the Acne-ID study
Around 1 in 10 young people have severe acne that can cause scarring. Isotretinoin is a powerful medicine that clears acne, but it often causes unpleasant side effects. The Acne-ID study tests whether taking a lower daily dose works just as well while causing fewer side effects.
United Kingdom · England · Scotland - completedPhase IV
An 8-week study to investigate the benefits of a blue LED facial mask device on acne
This 8-week study looks at whether a blue LED light mask helps improve acne. We need around 30 healthy volunteers aged 14-75. It involves clinic visits for skin checks and photos, and using the mask at home. The goal is to understand how this device works for future users.
United Kingdom · Wales - recruiting
Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital
This study at Nantes University Hospital is looking at people with acne. It aims to understand the condition better, see what treatments work best, and explore how acne affects daily life and mental well-being. It's the first study of its kind in France.
France - recruitingPHASE1, PHASE2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
This study is testing a new mRNA vaccine for moderate to severe acne in adults aged 18-45. We want to see if it's safe, if it helps reduce acne, and how the body reacts to it, to find the best dose.
United States · Australia · Canada - recruitingNA
Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial
This study looks at whether a daily probiotic drink can help women aged 40-60 with skin issues like eczema or rosacea. We want to see if it can reduce inflammation and improve their immune system during menopause.
United Kingdom