- authorisedTherapeutic confirmatory (Phase III)
"MetCool ACS"- Metformin "Cooling" Effect on metformin-naive Patients Treated with PCI because of Acute Coronary Syndrome
This study looks at whether metformin, a common diabetes drug, can help patients who have had a heart attack and recently had a procedure to clear their blood vessels. Researchers want to see if it reduces the need for more heart-clearing procedures later on.
Poland - ongoing, recruitingPhase III and phase IV (Integrated)
RE-DUAL TICLO PCI: Dual Therapy with dabigatran/ticagrelor versus Dual Therapy with dabigatran/clopidogrel in ACS patients with indication for NOAC undergoing PCI.
This study looks at two different ways to combine medicines for people who have had a heart attack and need a procedure to unblock their heart arteries. It aims to find out which combination is safer in terms of causing less bleeding, while still preventing blood clots.
Netherlands - recruiting
Barts Sex-CAD Database - Sex Hormones and Inflammatory Status in Coronary Artery Disease
This study looks at how hormones and inflammation affect heart artery disease in men and women, especially for women after menopause. Researchers at Barts Heart Centre hope to find better ways to treat heart conditions by understanding these differences.
United Kingdom - active not recruitingNA
LEADERS FREE II: BioFreedom™ Pivotal Study
This study is looking at a special stent called BioFreedom™ for people with heart problems who are at a higher risk of bleeding. It aims to see if this stent, with a short course of blood-thinning medicine, works as well as other common treatments.
United States · Canada · Denmark - recruiting
The Harefield Acute Myocardial Infarction Cohort
This study at Harefield Hospital collects blood and health information from patients having a heart attack. Researchers want to find new ways to understand and treat heart conditions by looking at inflammation and germs in blood samples.
United Kingdom - active not recruiting
Point of Care Evaluation of High-sensitivity Cardiac Troponin
This study is testing a new, rapid finger-prick test to help doctors quickly find out if someone arriving at the hospital with chest pain is having a heart attack. It aims to get results in about 10 minutes, much faster than current methods, helping patients get the right care sooner.
United Kingdom - authorisedTherapeutic use (Phase IV)
Combined impact of cardiovascular polypill treatment and a specific nurse education program on adherence to therapy in patients with ACS: a randomized study
This study looks at how well people with a recent heart problem take their medicines. It also checks if a special medicine (a 'polypill') and nurse support help them stick to their treatment. Researchers want to see if these things improve heart health.
Spain - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-Blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome
Netherlands · Latvia · Denmark