- ongoing, recruitingTherapeutic use (Phase IV)
Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial
This study, called WATERLAND, is comparing two common fluid treatments, normal saline and lactated Ringer's solution, for people with sudden inflammation of the pancreas (acute pancreatitis). Researchers want to see which fluid best prevents serious complications in the first month after treatment starts.
Spain · France - authorisedTherapeutic use (Phase IV)
Normal saline versus lactated Ringer’s solution for fluid administration in acute pancreatitis, an open-label multicenter randomized controlled trial: the WATERLAND trial
This study, called WATERLAND, is looking at which fluid drip is better for people with acute pancreatitis. It compares two common fluid types to see if one helps more by causing fewer serious problems or side effects.
Hungary - recruitingPHASE2
Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial (RAPID-I)
This study is looking at whether a drug called infliximab can help treat acute pancreatitis (a sudden inflammation of the pancreas). We want to see if it's safe and effective in reducing the impact of this serious condition. Participants will receive either infliximab or a dummy drug.
United Kingdom - not yet recruitingNA
Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis
This study looks at a new device called NucleoCapture for people with severe pancreatitis. It aims to see if this device is safe and can reduce harmful substances in the blood to help patients recover better. It compares those using the device with those receiving standard care.
United Kingdom - enrolling by invitationNA
Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis
This study compares a new device, the EndoRotor, with standard methods for clearing infected fluid collections in the pancreas. It aims to find out if the new device is better for treating a condition called 'walled off necrosis' in people with severe pancreatitis.
United States · Denmark · Germany