Acute Respiratory Distress Syndrome research hub
9 indexed studies · 5 currently recruiting
- recruitingPHASE2, PHASE3
Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome
This study looks at how different types of ongoing sedation affect breathing and lung health in seriously ill patients. We're comparing standard IV sedation with inhaled sedation, often used in surgery, to see which helps patients on breathing machines breathe better and protect their lungs.
United Kingdom - recruiting
ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)
This study looks at how well children recover after needing a special life support machine (ECMO) for serious breathing problems (ARDS). It also compares how different ways of starting ECMO affect children's health, learning, and quality of life.
United States · Australia · Canada - ongoing, recruitingTherapeutic exploratory (Phase II)
Phase 2, proof-of-concept, randomized, double-blinded, placebo-controlled, multicenter study to assess efficacy and safety of reparixin as add-on therapy to standard of care in adult patients with Acute Respiratory Distress Syndrome (RESPIRATIO)
This study is testing a new tablet medicine called reparixin for adults with serious lung problems (Acute Respiratory Distress Syndrome or ARDS). We want to see if it helps improve breathing when given with usual care, and if it's safe.
Italy · Germany - enrolling by invitation
The Medical Management in Patients Exposed to Weapons of Mass Destruction
This study looks back at how medical teams have responded to major incidents involving dangerous substances over the past 50 years, and will continue to observe future events. It aims to understand how injured people were cared for from the scene of the incident to the hospital.
United States · Canada · Czechia - recruitingPHASE2
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
This study is testing a new medicine, Rhu-pGSN, for people with severe breathing problems (ARDS) caused by infections. It will compare the new medicine to a dummy treatment (placebo) to see if it's safe and helps people recover better.
United States · Belgium · Bulgaria - active not recruitingNA
Influence of NEP Inhibition on Vascular Leak and Inflammation (NEPi-INFLAMMATION)
This study looks at a new way to treat Acute Respiratory Distress Syndrome (ARDS), a severe lung condition. We're testing a drug, Racecadotril, on healthy volunteers. It may help stop fluid leaking into the lungs, a major problem in ARDS, by boosting a natural substance called CNP.
United Kingdom - active not recruitingPHASE1, PHASE2
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST)
This study, REALIST, investigates a new treatment for Acute Respiratory Distress Syndrome (ARDS), a severe lung condition where fluid builds up, often affecting critically ill patients. It tests if special cells from umbilical cord blood can help improve lung function and safety compared to a dummy treatment.
United Kingdom - authorisedTherapeutic confirmatory (Phase III)
APROTININ TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME: A MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE III TRIAL
This study is looking into a treatment called aprotonin for a serious lung condition called Acute Respiratory Distress Syndrome (ARDS). It compares aprotonin to a dummy treatment to see if it helps patients breathe better without a ventilator.
Spain - recruiting
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
This study looks at why some critically ill patients who need life support (ECMO) stay weak after leaving intensive care. We want to understand this weakness and how it affects their daily lives and well-being after severe heart and lung problems.
United Kingdom