Advanced melanoma with brain metastases, PD-1 refractory or PD-1 naive research hub

A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02D

This study, called KEYMAKER-U02, is for adults with advanced melanoma, a type of skin cancer, that has spread to the brain. It's looking at new ways to treat this cancer, sometimes using a drug called pembrolizumab (Keytruda) alone, or in combination with other medicines like Lenvatinib or MK-1308A.