Research.Patient.info
Advanced MTAP-null solid tumors research hub
2 indexed studies · 1 currently recruiting
- recruitingPhase I and Phase II (Integrated)- First administration to humans
A phase 1/1b/2 study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AMG 193 alone and in combination with docetaxel in subjects with advanced MTAP-null solid tumors
This clinical trial is testing a new experimental medicine called AMG 193 for adults with advanced solid tumours. It focuses on cancers that lack a specific gene known as MTAP. Researchers want to find a safe dose and see whether the drug can help shrink or control cancer.
Belgium · Germany · Austria - active not recruitingPHASE1, PHASE2
A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)
This study is testing a new medicine, Anvumetostat, for people with advanced cancers that are missing a specific gene called MTAP. Researchers want to find the safest dose, see how well it works, and understand its side effects, sometimes given with another cancer drug called Docetaxel.
United States · Australia · Austria