- not yet recruitingNA
Towards a Targeted Ultrasound Neuromodulation Intervention for Alcohol Abuse Disorders
This study is testing a new way to help people with alcohol use disorder, sometimes called alcohol addiction. It uses gentle sound waves, like those used in scans, to target specific brain areas. The aim is to see if this can help reduce cravings and improve control over drinking.
United Kingdom - recruitingPHASE3
A Study of Brenipatide in Participants With Alcohol Use Disorder
This study is looking into a new medication called brenipatide for people with alcohol use disorder. It aims to see if it's safe and helps people reduce or stop their drinking, compared to a dummy treatment.
United States · Belgium · China - not yet recruiting
Exploration of Acceptability of Alcohol Interventions
This study looks at how staff feel about using certain alcohol support methods and how well people from different backgrounds connect with an NHS alcohol service in North West England. It helps understand why some people get support and others don't.
United Kingdom - recruitingNA
Deep Brain Stimulation to Understand and Treat Addiction
This study is looking at whether a treatment called deep brain stimulation (DBS) can help people with severe alcohol use disorder. DBS uses gentle electrical signals to change brain activity. The aim is to see if it can reduce drinking for those who haven't been helped by other treatments.
United Kingdom - recruiting
Nottingham Community Liver Biomarkers Cohort
This study in Nottingham looks at improving how we find liver disease early in the community. It involves people with risk factors like heavy alcohol use, obesity, or diabetes, to see if new blood and scan tests can help identify liver problems before they become serious.
United Kingdom - authorisedPhase II and Phase III (Integrated)
CIRAANO: Multimodal exploration (including radiopharmaceuticals Amyvid® and Tauvid®) of theater actors, memory athletes, and patients with various memory pathologies: evaluation of mnesic strategies and their cerebral substrates, and contribution to the treatment of memory pathologies.
This study looks at memory in different groups, including actors, memory athletes, and people with memory problems like Alzheimer's. It uses special brain scans to understand how different memory strategies work in the brain and how this might help treat memory conditions.
France - active not recruitingNA
Probiotic Study in Alcohol Recovery
This study looks at whether a daily probiotic capsule can help people who want to reduce their alcohol use. It aims to see if these 'good bacteria' can lessen cravings and improve mood, thinking, and overall well-being in adults who drink alcohol heavily.
United Kingdom - recruitingPHASE3
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
This study is looking at a new medicine called brenipatide for people with moderate to severe alcohol use disorder. It compares brenipatide to a dummy medicine (placebo) to see if it's safe and effective in helping people cut down or stop drinking.
United States · Belgium · China - ongoing, recruitingTherapeutic exploratory (Phase II)
Does the Glucagon-like Peptide 1 (GLP-1) receptor agonist semaglutide reduce alcohol intake in patients with Alcohol Use Disorder and comorbid obesity?
Denmark - ongoing, recruitingTherapeutic exploratory (Phase II)
Psilocybin in alcohol use disorder with comorbid depression - Randomized double-blind controlled pilot study.
France - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A phase 1, open-label, cross-over study in healthy volunteers to assess the pharmacokinetic profile of Prazosin and Cyproheptadine following single dose oral administration of KT110 tablet and following administration of Alpress and Periactine marketed tablets
France