ALS / Amyotrophic Lateral Sclerosis research hub
4 indexed studies · 4 currently recruiting
- recruitingTherapeutic confirmatory (Phase III)
Magnet Study - A Multi-arm, Adaptive, Group-sequential trial NETwork to evaluate drug efficacy in patients with Amyotrophic Lateral Sclerosis (ALS)
The Magnet Study is looking into a drug called Lithium for people with ALS (also known as Motor Neurone Disease). It aims to see if Lithium can help people live longer or stop their breathing from getting worse. They will compare it to a dummy pill.
Sweden · Netherlands · Spain - recruiting
7T Imaging Pilot-study in Patients With Motor Neuron Disease to Find Non-Invasive Disease Imaging Biomarkers
This study uses a super-powerful MRI scanner to look at the brains of people with Motor Neuron Disease (MND). The goal is to find new ways to diagnose MND earlier and more accurately, helping patients get the right care and join trials sooner. It’s a small pilot study to see if this new scan works well.
United Kingdom - not yet recruiting
Characterization of Platelet Molecular Profiles in ALS for the Identification of Specific Diagnostic Biomarkers - A Pilot Study
This study aims to find new ways to diagnose ALS early by looking at special markers in blood platelets. Researchers hope to tell ALS apart from similar conditions and speed up how quickly people get a diagnosis, leading to better care.
France - recruitingPHASE1
A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis
This study looks at a new medicine called LY4256984 for people with ALS, also known as Motor Neurone Disease. We want to see if it's safe, what side effects it might cause, and how the body handles it. It's given as an injection into the spine.
Belgium · Canada · Germany