Alzheimer's disease (AD) research hub
5 indexed studies · 5 currently recruiting
- recruitingTherapeutic exploratory (Phase II)
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of ABBV-916 in Subjects with Early Alzheimer's Disease
This study is looking into a new medication for early Alzheimer's disease. Researchers want to see if it's safe and helps reduce certain changes in the brain that are linked to the condition. It's a key step in understanding potential new treatments.
Portugal · Italy · Spain - recruitingHuman Pharmacology (Phase I)- Other
A Study to Assess Distribution, Binding, and Retention of the Monoclonal Antibody Trontinemab in the Brain of Healthy Participants and Patients with Alzheimer’s Disease
This early-stage study tests a new medicine called trontinemab for Alzheimer's disease. Researchers want to see how well the medicine reaches the brain, how it attaches to its target, and how long it stays there. The trial welcomes both healthy adults and people diagnosed with Alzheimer's disease aged 18 and over.
Netherlands - recruiting
Early detection tools for Alzheimer's disease: a multi-site observational study
This European study looks at new ways to detect Alzheimer’s disease much earlier. Researchers are testing simple digital memory games on phones or computers alongside routine blood tests. People aged 40 and over, both with and without memory problems, can take part to help improve future NHS brain care.
United Kingdom · England · Finland - recruitingNA
COGSCREEN II: Early Detection of Cognitive Impairment
This study, COGSCREEN II, aims to find better ways to spot early signs of Alzheimer's disease in people aged 60 and over. It works with local doctors to test new digital and blood tests for early detection, hoping to help people get the right treatments sooner.
Germany - recruiting
Amyloid-β Clearance Mechanisms in Alzheimer's Disease
This study looks at how the brain clears away a protein called amyloid-beta, which builds up in Alzheimer's disease. Researchers are using special brain scans to understand how different body systems, like the blood-brain barrier and brain's 'waste disposal' system, work to remove this protein.
Germany