- recruitingPHASE1, PHASE2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
This study is testing a new cell therapy (AZD0120) for people with AL amyloidosis that has come back or not responded to previous treatments. It aims to see how safe and effective the treatment is.
United States · Canada · United Kingdom - not yet recruitingNA
Impact of a Cardiac Rehabilitation Program on Patients With Cardiac Amyloidosis
This study looks at how a special exercise and activity programme, called cardiac rehabilitation, helps people with a heart condition called cardiac amyloidosis. We want to see if it improves their ability to exercise and their overall quality of life.
France - active not recruitingPHASE2
A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis
This study looks at new drug combinations for a serious condition called AL amyloidosis, which affects the heart. We want to see how safe these treatments are for the heart and how they work in different people, especially those from diverse backgrounds.
United States · Canada · China - recruitingPHASE3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
This study looks at a new drug, acoramidis, for people who have a faulty gene that can cause a condition called ATTR. It aims to see if the drug can stop or slow down the disease from developing in people who don't yet have symptoms.
United States · Argentina · Australia