- recruitingPHASE4
Pediatric Long-Term Follow-up and Rollover Study
This study looks at the long-term well-being of children and young people who have been treated with specific medications (dabrafenib and/or trametinib) for certain brain cancers in previous clinical trials. It aims to understand the lasting effects of these treatments.
United States · Argentina · Australia - recruitingPHASE2
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
This study is looking at new drug combinations to treat certain types of brain tumours in children and young adults. It aims to see if combining ribociclib with either everolimus or temozolomide can help patients live longer and improve their health.
United States · Australia · Canada - recruiting
Targeted Pediatric High-Grade Glioma Therapy
This study aims to understand childhood brain tumours better by looking at their genes. For children, teenagers, and young adults with newly diagnosed high-grade gliomas, including DIPG, doctors will check their tumour's genetic makeup to see if they might be suitable for specific new treatments in future trials.
United States · Australia · Canada