Aortic Valve Calcification research hub
5 indexed studies · 3 currently recruiting
- authorisedTherapeutic confirmatory (Phase III)
Does Colchicine Reduce Progression of Aortic Valve Stenosis? Colchicine and Inflammation in Aortic Stenosis (CHIANTI): A placebo-controlled, double-blind, multicenter randomized trial.
This study looks at whether a widely used medicine called colchicine can slow down the hardening of the heart's aortic valve. Researchers will compare people taking colchicine with those taking a dummy pill, to see if it helps keep the valve working better for longer. It's a big study to find out if this treatment could be useful.
Netherlands - recruiting
Valved Graft PMCF Study
This study looks at how well a new type of heart valve called an 'Abbott Valved Graft' works in people with certain heart conditions. Doctors want to see if it's safe and effective after it's been used in patients in many hospitals around the world.
United States · Austria · Denmark - not yet recruiting
Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure)
This study looks at how your body's defence system (immune system) reacts during and after heart valve surgery. Researchers want to see if a stronger immune response means a quicker recovery and fewer problems like infections.
United Kingdom - active not recruiting
Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)
This study looks at the safety and performance of a specific heart valve replacement, the On-X Aortic Prosthesis, after it's been used in patients. Doctors observe how patients are doing during their routine check-ups. It helps us understand how well the valve works in real-world situations.
United States · Germany · Italy - recruiting
Assessment of Lipoprotein(a) and Endogenous Fibrinolysis in Atherosclerotic Cardiovascular Disease/Aortic Valve Disease
This study looks at a blood fat called Lp(a) and how well your body breaks down blood clots, especially in people with heart or aortic valve disease. We're also checking if new cholesterol medicines can help improve clot breakdown.
United Kingdom