- active not recruiting
Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)
This study looks at the safety and performance of a specific heart valve replacement, the On-X Aortic Prosthesis, after it's been used in patients. Doctors observe how patients are doing during their routine check-ups. It helps us understand how well the valve works in real-world situations.
United States · Germany · Italy - not yet recruitingNA
A Prospective Multicenter Pivotal Study to Evaluate Safety and Effectiveness of Venus-Neo Surgical Aortic Valve
This study is testing a new heart valve called Venus-Neo to see if it's safe and works well for people needing aortic valve replacement. Researchers will follow participants for five years to understand its long-term performance.
Germany - not yet recruiting
TAVIS Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease
This study looks at a new way to treat problems with the heart's aortic valve, called TAVI, using the Trilogy Heart Valve System. It helps doctors understand how well this treatment works for people with a narrowed or leaky aortic valve. It's for patients aged 18 and over.
Germany - enrolling by invitationNA
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
This study is looking at a new heart valve replacement called Navitor TAVI. It wants to see if it's safe and works well for people with a common heart problem called severe aortic stenosis, which narrows a main heart valve. It's for adults at different surgical risks.
United States · Australia · Belgium - not yet recruiting
KONECT RESILIA Aortic Valved Conduit (AVC) Real-world Study Assessing Safety and Performance
This study looks at how well a new type of heart valve called KONECT RESILIA works in people who need both their aortic valve and a part of their main heart artery (aorta) replaced. It's for people aged 18 and over in Europe and Canada.
Germany - active not recruiting
SJM Masters HP 15mm Rotatable Mechanical Heart Valve as Aortic Valve Replacement Therapy
This study looks at a special small mechanical heart valve (15mm) when used in children needing a new aortic valve. Researchers are checking how safe and well it works over a long time to help children with heart valve problems.
United States · Germany - recruitingNA
TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics
This study looks at how the position of a new heart valve after a TAVR procedure affects blood flow and important arteries. It also checks if new scanning methods can give us the same information as current ones, helping doctors fine-tune future treatments.
Germany - not yet recruiting
Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure)
This study looks at how your body's defence system (immune system) reacts during and after heart valve surgery. Researchers want to see if a stronger immune response means a quicker recovery and fewer problems like infections.
United Kingdom - recruiting
Valved Graft PMCF Study
This study looks at how well a new type of heart valve called an 'Abbott Valved Graft' works in people with certain heart conditions. Doctors want to see if it's safe and effective after it's been used in patients in many hospitals around the world.
United States · Austria · Denmark - recruiting
Assessment of Lipoprotein(a) and Endogenous Fibrinolysis in Atherosclerotic Cardiovascular Disease/Aortic Valve Disease
This study looks at a blood fat called Lp(a) and how well your body breaks down blood clots, especially in people with heart or aortic valve disease. We're also checking if new cholesterol medicines can help improve clot breakdown.
United Kingdom