- authorisedTherapeutic exploratory (Phase II)
A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Soquelitinib in Moderate to Severe Atopic Dermatitis (SIERRA1)
This clinical study tests an experimental tablet called soquelitinib for adults with moderate to severe atopic dermatitis, also known as eczema. Researchers want to see if the medicine is safe, easy to take, and able to reduce skin redness, dry patches, and itchy symptoms compared to a dummy tablet.
Italy · Czechia · Germany - recruitingHuman Pharmacology (Phase I)- Other
The effect of SYX-5219 on an immune response in the skin.
This study is looking at a new medicine called SYX-5219. It aims to understand how this medicine affects the skin's immune system in people with eczema (atopic dermatitis). Researchers want to see if it can help reduce the body's reaction that causes eczema symptoms.
Netherlands - completedPhase II
A study of JNJ-95475939 in the treatment of participants with moderate to severe atopic dermatitis
This study is testing a new medicine, JNJ-95475939, for moderate to severe eczema (atopic dermatitis). Researchers want to see how well it works and if it's safe compared to a dummy treatment and an existing medicine. It involves adults aged 18 and over.
United Kingdom · Argentina · Brazil - recruitingNA
Effect of Partially Hydrolyzed Formula With Synbiotics on Skin Barrier Function
This study looks at a special baby formula with added good bacteria to see if it can help prevent eczema (atopic dermatitis) in babies who might be at risk of allergies. They want to see if it protects their skin.
Belgium · France · Germany - active not recruitingNA
Effectiveness of Psychodermatologic Educational Modules on Atopic Dermatitis Patient Outcomes
This study looks at how educational materials about the psychological impact of eczema can help people manage their condition better. We want to see if these online resources improve how severe eczema is and how much it affects daily life, for people aged 4 and over. This will help create better support for patients.
Canada - not yet recruitingNA
Moisturization and Skin Hydration Study
This study looks at the best way for young people with eczema to use moisturiser. We're comparing putting it on in the shower/bath versus after drying, to see which helps skin and itching more, and which method people prefer.
Canada