- recruitingPHASE3
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
This study is looking at a new combination of medicines, sonrotoclax plus zanubrutinib, for adults in the UK with a type of blood cancer called Mantle Cell Lymphoma. It aims to see if this combination works better and is safe when their cancer has come back or isn't responding to other treatments.
United States · Argentina · Australia - not yet recruitingPHASE1
A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )
This study is testing a new drug, LY4152199, for people with certain types of B-cell lymphoma that have returned or not responded to previous treatments. Researchers want to find the best dose and see how safe and effective it is.
United States · Australia · Canada - ongoing, recruitingPhase I and Phase II (Integrated)- Other
A Phase 1/2, Open-Label, Multicenter Study to Investigate the Safety, Pharmacokinetics, and Efficacy of Fadraciclib (CYC065), an Oral CDK2/9 Inhibitor, in Subjects with Advanced Solid Tumors and Lymphoma.
This study is testing a new medicine called Fadraciclib for advanced cancers like endometrial, ovarian, and some lymphomas. It aims to see if it's safe, how it works in the body, and if it can shrink tumors or stop cancer growth. It's for adults aged 18 and over.
Spain - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A safety study of PF-08046045/SGN-35T in adults with advanced cancers
This study is looking at a new medicine for people with certain advanced cancers, including different types of lymphoma. It's the first time this medicine is being given to people, to check if it's safe and how it works in the body.
Germany · Spain · Denmark