- recruitingTherapeutic confirmatory (Phase III)
A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia Who Have Undergone a Kasai Hepatoportoenterostomy (BOLD)
This clinical study is testing a medicine called odevixibat in children with biliary atresia who have had a Kasai operation. Researchers want to see if taking this daily medicine can protect the liver, improve bile flow, and delay or prevent the need for a liver transplant over two years.
Hungary · Belgium · France - recruiting
The Dirty Nappy Study
The 'Dirty Nappy Study' investigates if a computer program can spot liver problems like cholestasis and biliary atresia in babies early. Parents take photos of their baby's dirty nappies, and the program analyses them. Early detection could lead to better outcomes for babies.
United Kingdom - active not recruitingPHASE3
Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)
This study is testing a new medicine, Odevixibat, for babies with a liver problem called Biliary Atresia. It aims to see if the medicine is safe and helps after a special operation called a Kasai procedure.
United States · Australia · Belgium