Non-small Cell Lung Cancer research hub
7 indexed studies · 4 currently recruiting
- recruitingPHASE1, PHASE2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
This study is testing a new medicine called S241656 for people with certain advanced cancers, including lung, bowel, and pancreatic cancers. It aims to find a safe and effective dose, either alone or with other treatments, for cancers with specific genetic changes.
United States · Denmark · Hong Kong - recruitingNA
Feasibility of a Cognitive Stepped Care Program for Adults With Brain Metastases
This study looks at a new way to help people with brain metastases manage memory, thinking, and concentration problems. It's called the Cognitive Stepped Care Program (CSCP) and aims to improve their quality of life.
Canada - recruitingNA
The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases?
This study looks at how best to treat people with several brain tumours, often from other cancers. It compares two types of radiation treatment to see which offers a better quality of life and helps people live longer, while also being easier to tolerate.
Germany - recruiting
Metachronic Brain Metastases After Esophagectomy for Esophageal Cancer (METABREC)
This study, called METABREC, looks back at medical records of people who had surgery for gullet cancer. It aims to understand how often cancer spreads to the brain after surgery and what might increase this risk.
United States · Belgium · France - active not recruitingPHASE2
Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC
This study compares using a drug called osimertinib alone, or osimertinib with focused radiation (SRS), for lung cancer that has spread to the brain. It's for people whose lung cancer has a specific genetic change (EGFR positive) and haven't had previous treatment for it.
Canada - active not recruitingNA
Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases
This study compares three types of radiotherapy for brain metastases (cancers that have spread to the brain) to see which works best. Doctors want to know if giving radiation before, during, or after surgery is most effective and has the fewest side effects.
Germany - active not recruiting
Measuring and Mapping Cognitive Decline After Brain Radiosurgery
This study looks at how focused brain radiation (SRS) affects brain function and quality of life in people with brain tumours. Researchers want to find out which brain areas are most affected so they can improve future treatments and reduce side effects.
United Kingdom