Glioblastoma research hub

ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids

The Use of 5-ALA in Paediatric Patients With High Grade Brain Tumours

This study looks at a special dye, 5-ALA, to help surgeons remove brain tumours in children aged 3-18. It aims to see if 5-ALA is safe and helps doctors see the tumour more clearly, to remove as much as possible while protecting healthy brain tissue.

FIH Clinical Investigation of Graphene Electrodes for Brain Mapping

This study tests new, very thin brain sensors made from a material called graphene. Doctors want to see if these sensors are safe and work well during brain tumour surgery to help protect important brain functions.

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

This study is testing a new oral medicine, APL-101, for people with advanced cancers. It focuses on lung cancer and other solid tumours where specific genetic changes linked to a protein called MET are found. Researchers want to see how well it works and if it's safe.

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

The MOMENTUM Study is tracking how a new type of advanced radiotherapy, called MR-Linac, works for people with different cancers. It aims to see if this treatment improves survival, controls cancer better, and enhances quality of life by using highly precise radiation guidance.

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

This study compares a new drug (niraparib) with standard treatment (temozolomide) for a type of brain tumour called glioblastoma. We want to see if niraparib can help people live longer. Participants will take medication daily alongside radiotherapy.