Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis research hub

J4G-MC-JZVD - FORAGER-2: A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Vepugratinib Combined with Enfortumab Vedotin and Pembrolizumab in Adults with Untreated Locally Advanced or Metastatic Urothelial Carcinoma with an FGFR3 Genetic Alteration.

This study is testing a new combination of medicines for adults with a certain type of bladder cancer that has spread or is advanced. It aims to see how well these new drugs work together and if they are safe when used for bladder cancer with a specific genetic change.