Children with refractory symptoms research hub

SETRAPED : A prospective, multicenter study evaluating the efficacy and tolerance of transmucosal midazolam for proportionate palliative sedation in children with refractory symptoms

This study looks at a gentle medicine called midazolam to help very sick children who are receiving palliative care. Doctors want to see if giving this liquid medicine inside the mouth can safely soothe severe distress and pain when other standard treatments have not brought enough comfort.