- recruitingNA
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
This study looks at a procedure called renal denervation to treat high blood pressure. It aims to see if a simpler way of doing the procedure is just as good, and possibly quicker, than older methods. This could offer a new option for people whose blood pressure is hard to control.
Australia · Belgium · Germany - recruitingNA
Telemonitoring of Hypertensive Patients With Chronic Kidney Disease
This study looks at using a home blood pressure monitor that sends readings to a doctor for people in remote areas with high blood pressure and kidney disease. It compares this system with extra support versus just sharing results with their usual doctor, aiming to improve blood pressure control.
Canada - recruiting
DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve
This study looks for better ways to measure how well kidneys work, especially in early kidney disease. It compares new tests with current methods to see how kidneys respond to stress, like after eating protein, aiming for earlier detection and better understanding of kidney health.
United Kingdom - recruiting
LONGitudinal Multi-omics Phenotyping of KIDney Function Alteration
This study looks at how a new kidney transplant affects kidney function, the body's immune system, and gut bacteria in both the person receiving the kidney and the donor. Researchers will follow them before and after the transplant.
Germany - active not recruiting
National Unified Renal Translation Research Enterprise - Chronic Kidney Disease
This study looks at how chronic kidney disease (CKD) progresses. We aim to find better ways to predict who might develop serious kidney problems, heart attacks, or strokes, so we can give them the best care. Participants will help us understand CKD better.
United Kingdom - recruitingPHASE3
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
This study, called Proact, is investigating a new treatment called REACT (also known as rilparencel) for people with type 2 diabetes and chronic kidney disease. Researchers want to see if this treatment can help kidney function and if it is safe.
United States · Australia · Canada - recruiting
Chronic Kidney Disease - REAL Life Study in Alsace
This study in Alsace, France, looks at people with severe kidney disease to understand their health journey better. By collecting real-life information, researchers hope to improve care and understand what affects the condition before dialysis or transplant are needed.
France - recruitingPHASE3
Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
This study looks at two medicines, tranexamic acid and desmopressin, to see if they can reduce serious bleeding in people with kidney disease who are having surgery. It's a first step to see if a bigger study should be done.
Canada - active not recruitingPHASE1
The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol
This study looks at how your body handles cannabis components (THC and CBD) when taken by mouth. It includes healthy people and those with kidney disease, including those on dialysis, to understand how kidney health affects these compounds.
Canada - active not recruiting
Multimorbidity and Sarcopenia Feasibility Study in Chronic Kidney Disease
This study looks at how muscle and fat change in people with kidney disease compared to healthy individuals. We want to understand why muscle loss is common in kidney disease, hoping to find better ways to help people and improve their health.
United Kingdom - recruitingPHASE2
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
This study looks at a medicine called difelikefalin for teenagers (12-17) on dialysis who have very itchy skin from kidney disease. It checks if the medicine is safe and how much gets into their blood. We hope to find a new way to help young people with this problem.
China · Greece · Israel - recruiting
Diurnal BP Patterns in Those at Increased Risk of CVD
This study looks at how blood pressure changes during the day and night in people who have a higher chance of developing heart and blood vessel problems, especially those with kidney conditions. We want to understand these patterns better to help doctors give the best possible care.
United Kingdom - recruitingNA
Automated Insulin Delivery in Adults With Advanced Kidney Disease
This study looks at a new system called automated insulin delivery (AID) for people with diabetes and advanced kidney disease. It checks if AID can improve blood sugar control and quality of life compared to usual care. It's a small study in London for people injecting insulin.
United Kingdom - recruiting
Registry of GORE® ACUSEAL Vascular Graft in Dialysis Access
This study looks at a special tube, called a GORE ACUSEAL Vascular Graft, used for dialysis in people with severe kidney disease. Researchers want to see if it's safe and works well over two years to help patients get their dialysis.
Germany · Italy · United Kingdom - active not recruitingNA
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
This study looks at a treatment called renal denervation (RDN) for high blood pressure. It uses a device called Symplicity Spyral to see how well it works and if it's safe in the long term, especially for people whose blood pressure is hard to control.
United States · Australia · Belgium - active not recruiting
Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease
This study looks at a special MRI scan for people with long-term kidney problems. We want to see if this scan can help us understand kidney disease better, predict how it might change, and guide treatment, hoping to improve care for patients.
United Kingdom - recruiting
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
This study aims to understand why common medicines don't work the same for everyone in the UK, especially for people from different backgrounds. It will look at many health conditions, hoping to improve how we treat them and make healthcare fairer for all.
United Kingdom