- recruitingTherapeutic exploratory (Phase II)
A phase 2, multicenter, randomized, double blind, active controlled, parallel group study assessing the analgesic effect and safety of two doses of DFL24412 in patients with chronic low back pain compared to Ketoprofen Lysine Salt (KLS)
This study is testing different doses of a new medicine (DFL24412) for long-lasting lower back pain. Researchers want to see if it reduces pain and is safe, comparing it to a common painkiller called Ketoprofen Lysine Salt.
Italy · Spain - completedNot Applicable
Can blocking the nerve to the back muscle predict the outcome of stimulating back muscles in managing pain due to muscle dysfunction?
This study tests whether temporary nerve-numbing injections can predict if a small implanted device, called ReActiv8, will help relieve long-term lower back pain. The device gently stimulates deep back muscles to rebuild strength and stability. The trial is taking place at Leeds Teaching Hospitals NHS Trust.
United Kingdom · England - recruitingNA
Study of the Contribution of Osteopathic Treatment to Classic Medical Management in Patients With Chronic Low Back Pain
This study looks at whether adding osteopathic treatment to usual medical care can help people in the UK with long-term back pain feel better. Researchers compare different approaches to see if combining treatments reduces pain more effectively over three months.
France - active not recruiting
Assessing Central Aspects of Pain
This study looks at new ways to understand long-lasting pain in conditions like arthritis and fibromyalgia. Researchers are using questionnaires and simple tests to see how the brain and nerves contribute to pain, aiming for better diagnosis and personalised treatments.
United Kingdom - recruitingNA
VRFR- Immersive Virtual Reality Use in a Spine Functional Restoration Program - A Feasibility Study
This study looks into using virtual reality (VR) with people who have ongoing lower back pain. We want to see if VR headsets are easy and helpful for both patients and healthcare workers in a special rehabilitation programme.
France - recruitingNA
Alberta Chiropractic SelfBack Study
This study is looking into how easy it is for chiropractors in Alberta, Canada, to offer a special app called SelfBack to their patients with ongoing back pain. The app gives personalised advice and exercises to help people manage their pain.
Canada - recruitingNA
The METRIC Study Protocol
This study looks at how spinal manipulation therapy (a type of hands-on treatment) helps people with long-term lower back pain. It aims to understand how it reduces pain and if treating the whole spine is better than just the lower back.
Canada