- recruitingPHASE3
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
This study looks at the long-term safety of a medicine called guselkumab for children and young people with Crohn's disease, ulcerative colitis, or a type of arthritis called juvenile psoriatic arthritis. It's for those who have already seen benefits from the medicine in an earlier study.
United States · Argentina · Australia - recruiting
A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)
This study looks at how well a medicine called guselkumab works for adults with moderate to severe Ulcerative Colitis or Crohn's Disease in the UK. Researchers want to see its real-world benefits and how different groups of patients respond.
United Kingdom - recruiting
A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis
This study looks at how well a medicine called etrasimod works for people in the UK with a bowel condition called ulcerative colitis. It follows patients receiving etrasimod as part of their usual care to see how their health changes over time.
Canada · Germany · United Kingdom - recruitingPHASE3
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
This study is testing a new medicine called Icotrokinra for teenagers and adults with moderate to severe ulcerative colitis. It aims to see how well it works, if it's safe, and if people can tolerate it, compared to a dummy pill.
United States · Argentina · Australia - active not recruitingPHASE3
A Long-term Extension Study of Ustekinumab in Pediatric Participants
This study looks at the long-term safety of a treatment called ustekinumab for children and young people with conditions like Crohn's disease or certain types of arthritis. It's for those already taking part in an earlier study of this medicine.
United States · Argentina · Belgium - active not recruitingPHASE2
Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis
This study is testing a new medicine, SAR443122, for adults with moderate to severe Ulcerative Colitis. We want to see how well it works and if it's safe compared to a dummy drug, and find the best dose.
United States · Argentina · Chile - active not recruitingPHASE1
A First-time in Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK4528287 in Healthy Participants
This study is testing a new medicine, GSK4528287, for bowel conditions like ulcerative colitis for the very first time in people. We want to see if it's safe, how the body handles it, and if it works as expected. We'll start with small doses in healthy volunteers.
United Kingdom - recruitingPHASE2, PHASE3
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
This study is testing a new medicine, ozanimod, for children aged 2-17 with moderate to severe ulcerative colitis that hasn't responded well to other treatments. We want to see if it helps them feel better and stay well.
United States · Australia · Belgium - active not recruitingPHASE2
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
This study looks at new ways to treat ulcerative colitis, a condition causing gut inflammation. We're testing a combination of medicines (JNJ-78934804) for people whose current treatments aren't working well. The goal is to see if these new approaches are safe and effective.
United States · Argentina · Australia - active not recruitingPHASE4
Determination of the Optimal Treatment Target in Ulcerative Colitis
This study is looking for the best way to treat ulcerative colitis (UC). We're testing different treatment goals to see which one works best at keeping your symptoms away, healing your gut, and improving your quality of life. Understanding this can help doctors treat UC more effectively.
United States · Belarus · Belgium - recruitingPHASE3
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
This study looks at a medicine called tulisokibart for Crohn's disease and ulcerative colitis. It's for people who were in earlier trials and found benefit from it. The aim is to check its long-term safety and how well it works over time.
United States · Czechia · France - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Phase 1 study on SAR443122 bioavailability and food effect in healthy adults
This early-stage study is looking at a new medicine called SAR443122 in healthy adults. It aims to understand how much of the medicine the body absorbs and if food affects this. We hope this research will eventually help people with ulcerative colitis.
Netherlands - authorisedTherapeutic exploratory (Phase II)
A multinational, multicenter extension study to investigate the long-term safety, tolerability and efficacy of balinatunfib in adults with Crohn’s disease or ulcerative colitis
This study looks at a new medicine called balinatunfib for adults with Crohn's disease or ulcerative colitis. It mainly checks for any side effects and how safe it is over a longer time. It also looks at if the treatment helps improve symptoms and gut health.
Belgium · Germany · Czechia - active not recruitingPHASE2
A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease
This study is looking at a new medication, TEV-48574, for adults with moderate to severe Crohn's disease or ulcerative colitis. It aims to see how well different doses work over the long term and if they are safe.
United States · Austria · Bulgaria