- recruitingNA
Biologics and Partial Enteral Nutrition Study
This study looks at whether adding special milkshakes to half your normal diet can help adults with Crohn's disease respond better to their usual medicine. It's for people starting a biologic injection for the first time.
United Kingdom - recruiting
Nutrition and Clinical Outcomes in IBD
This study looks at how nutrition and body health affect people with Crohn's disease and ulcerative colitis. We want to find better ways to check for poor nutrition and understand how it impacts treatment, surgery, and overall well-being in IBD patients.
United Kingdom - recruitingPHASE4
VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease
This study looks at new ways to treat Crohn's disease using a gentle scan called intestinal ultrasound. It aims to see if targeting 'transmural healing' – healing all layers of the bowel wall – alongside other measures, works better than standard care for people with moderately to severely active Crohn's.
United States · Australia · Belgium - recruitingPHASE2, PHASE3
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
This study is testing a new medicine, icotrokinra, for people in the UK with moderately to severely active Crohn's disease. Researchers want to see if it helps reduce symptoms and if it's safe to use, compared to a dummy medicine.
United States · Argentina · Australia - active not recruitingNA
Small Bowel Deep Learning Algorithm Project
This study uses a special computer program to help doctors find Crohn's disease in the small bowel more easily on MRI scans. It compares how well the computer does compared to experienced doctors looking at the scans.
United Kingdom - active not recruitingPHASE4
Stopping Aminosalicylate Therapy in Inactive Crohn's Disease
This study looks at whether people with Crohn's disease in remission can safely stop taking a common medicine called 5-ASA. It compares stopping the medicine with continuing it to see if symptoms stay away for at least two years.
Canada · Italy · Ukraine - recruiting
Fibrosis Associated Protein Inhibitor (FAPI) Radiotracer-based Imaging to Identify Fibrotic Intestinal Crohn's Disease
This study is testing a new way to see gut scarring in Crohn's disease using a special 'dye' and scans. Current treatments help inflammation, but not scarring. This new method could help doctors find scarring early and develop treatments to stop it.
United Kingdom - recruitingPHASE3
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
This study looks at a medicine called tulisokibart for Crohn's disease and ulcerative colitis. It's for people who were in earlier trials and found benefit from it. The aim is to check its long-term safety and how well it works over time.
United States · Czechia · France - active not recruitingPHASE3
A Long-term Extension Study of Ustekinumab in Pediatric Participants
This study looks at the long-term safety of a treatment called ustekinumab for children and young people with conditions like Crohn's disease or certain types of arthritis. It's for those already taking part in an earlier study of this medicine.
United States · Argentina · Belgium - recruitingNA
The CROCO Study: CROhn's Disease COhort Study
The CROCO Study looks at how Crohn's disease changes over time in people getting the latest treatments. We hope to understand the disease better and find ways to predict its impact, ultimately improving care for patients.
Belgium · Cyprus · Czechia - recruiting
Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study
This study looks at using robotic surgery for inflammatory bowel disease (IBD) like Crohn's disease and ulcerative colitis. Researchers want to see if robots can help surgeons operate more effectively and how this new method compares to traditional keyhole surgery for IBD.
United Kingdom - recruiting
NAZA - Nottingham/Astra ZenecA Prospective IBD Cohort Study
This study compares body markers linked to inflammation in people with Crohn's disease or ulcerative colitis (IBD) and healthy individuals. It aims to understand IBD better and find ways to predict treatment responses, ultimately leading to improved care.
United Kingdom - recruiting
PIBD-SETQuality: the Inception Cohort and Safety Registry
This study looks at how well current treatments work and their safety for children and teenagers with Inflammatory Bowel Disease (IBD). It wants to understand how individual factors might affect treatment outcomes and serious complications.
Netherlands · United Kingdom - recruiting
Diagnostic Concordance of MR Enterography and Ultrasound for Treatment Response Assessment in Crohn's Disease (MANTRA)
This study looks at how well two types of scans – MR Enterography (MRE) and intestinal ultrasound (IUS) – work to check if Crohn's disease treatment is effective. We want to see if they give similar results and if one scan is better or if they can be used interchangeably.
United Kingdom - active not recruitingPHASE2
A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease
This study is looking at a new medication, TEV-48574, for adults with moderate to severe Crohn's disease or ulcerative colitis. It aims to see how well different doses work over the long term and if they are safe.
United States · Austria · Bulgaria