Cutaneous lupus erythematosus research hub
4 indexed studies · 2 currently recruiting
- recruitingTherapeutic exploratory (Phase II)
A Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants with Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations.
This clinical trial is testing a new medicine called IMVT-1402 for adults with skin lupus. Researchers want to see if the drug is safe and effective at reducing rashes, redness, and swelling compared to a dummy treatment over 12 weeks. Taking part is completely voluntary.
Greece · Spain · Poland - authorisedTherapeutic confirmatory (Phase III)
LEISURE : Lenalidomide vs methotrexate in difficult-to-treat cutaneous lupus erythematosus (LEISURE trial): An assessor-blinded randomized clinical trial
This study, called LEISURE, is looking at two medicines, methotrexate and lenalidomide, to see which works best for people with severe skin lupus. Doctors want to see if these treatments can significantly reduce skin problems caused by lupus.
France - active not recruitingPHASE3
A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
This study is looking into a new treatment called anifrolumab for adults with a skin condition called cutaneous lupus erythematosus (CLE). It aims to see if anifrolumab is effective and safe compared to a dummy treatment.
United States · Argentina · Australia - recruitingPHASE3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
This study is looking into a new tablet medicine called Enpatoran for people with lupus that affects their skin. It aims to see if Enpatoran can help improve skin symptoms safely, compared to a dummy tablet or usual care. People aged 18-75 can take part.
United States · Australia · Brazil