Major Depressive Disorder (MDD) research hub
6 indexed studies · 5 currently recruiting
- recruitingPHASE3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
This study is looking into a new medication called CYB003 for adults with major depression. It aims to see if CYB003 is safe and effective when added to their current antidepressant treatment, compared to a dummy pill.
United States · Australia · Czechia - recruitingNA
Fluoxetine on Emotional Experience (FLEX) Study
This study looks at how a common antidepressant, fluoxetine, affects anger in healthy young people. Researchers will compare fluoxetine to a dummy pill to see if it changes how participants react to anger-related situations and if this shows in their body.
United Kingdom - enrolling by invitation
Evaluating the Effectiveness and Acceptability of a GPT-4o and RAG-Based Voice Chatbot for Depression Screening Using PHQ-9
This study is testing a new voice chatbot that uses advanced AI to screen for depression. It asks you questions about your mood and feelings and then gives you tailored advice. The aim is to see if this chatbot can help people check their mental health easily and accurately.
United Kingdom - active not recruiting
Measurement of Serum Inflammatory Markers in Patients Treatment-resistant Depression Given Psilocybin
This study looks at whether psilocybin, a compound from certain mushrooms, can help people with depression that hasn't responded to usual treatments. It focuses on whether psilocybin affects inflammation in the body, as inflammation might play a role in depression.
United Kingdom - recruiting
Investigating the Impacts of Early Life Experience on the Brain & Behaviour
This study explores how early life experiences can affect your brain, behaviour, and immune system as an adult. We want to understand why some early experiences lead to mental health challenges later on, helping us identify and support young people who might need help in the future.
United Kingdom - not yet recruiting
Mental Health Mission Mood Disorder Cohort Study
This study aims to understand why some people with depression respond to treatment better than others. It looks at various factors like symptoms, genes, and body chemistry to find new ways to improve diagnosis and treatment for mood disorders.
United Kingdom