Disorders characterized by a deficit in GABAergic signaling and cerebellar circuitry. research hub

PainCart Study Evaluating the Analgesic Profile of SAGE-319

This study is looking into a new medicine, SAGE-319, to see how it helps with pain. It's for people with certain health conditions where brain signals causing pain might not be working quite right. Researchers want to understand how this medicine works and if it can reduce pain.

A Randomized, Double-Blind (Sponsor-Unblinded), Placebo-Controlled, Single And Multiple Ascending Dose Study To Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Bioavailability and Food Effect (Open-Label) of Sage-319 in Healthy Adult Participants.