Dose escalation in healthy volunteers for subsequent Phase II trial of use in sickle cell disease and osteoarthritis research hub

Phase I clinical trial to determine maximum tolerable dose of African Bitter Root Food Supplement

This study looks at a traditional herbal remedy called African Bitter Root Supplement (ABRS). We want to find the highest amount that healthy people can take safely. This information will help us plan future studies on whether ABRS can help with conditions like sickle cell disease or osteoarthritis.