Cardiovascular Diseases research hub
14 indexed studies · 8 currently recruiting
- active not recruitingNA
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
This study looks at whether regular heart checks are really needed for people waiting for a kidney transplant. We want to see if skipping these extra checks after an initial one is just as safe as having them, focusing on preventing serious heart problems.
United States · Canada · Germany - active not recruitingNA
Xeltis Hemodialysis Access Graft: aXess Pivotal Study
This study is looking at a new type of graft, called the Xeltis aXess graft, for people with kidney failure needing dialysis. It aims to see if it's safe and works well for creating a connection that doctors can use for dialysis treatments.
Belgium · Germany · Greece - active not recruiting
Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)
This study is checking on people who had a special treatment (TX200-TR101) for kidney transplant rejection up to 15 years ago. Researchers want to see how everyone is doing long-term to make sure the treatment is safe and well-tolerated.
Belgium · Netherlands · United Kingdom - recruitingPHASE3
Efficacy and Safety of XyloCore Peritoneal Dialysis Solution.
This study looks at a new dialysis fluid called XyloCore for people with serious kidney disease. It compares XyloCore to standard fluids to see if it's safe and works well over six months, helping people on home dialysis.
Denmark · Germany · Italy - active not recruitingPHASE1, PHASE2
Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients
This study looks at a new treatment called TX200-TR101 for people getting a kidney transplant from a living donor. It aims to help the body accept the new kidney and prevent it from being rejected. Researchers want to check if it's safe and how well it works.
Belgium · Netherlands · United Kingdom - recruiting
Retrospective Analysis of Performance and Treatment Data Collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter & Genius 90 Concentrates in Haemodialysis Patients
This study looks back at information from patients who used special filters and solutions for kidney dialysis. Researchers want to understand how well these products worked to help people with kidney failure, especially for improving kidney function.
Germany - recruiting
Cardio-Renal Registry
This study is looking at patients with kidney disease heart problems. It aims to understand why heart issues are common in people with kidney conditions and how best to treat them. We hope to improve care for these patients.
United Kingdom - active not recruiting
VIRTUUS Children's Study
This study looks for new, gentle ways to check the health of kidney transplants in children. It aims to find early signs of problems like rejection or infection without needing a biopsy, helping transplanted kidneys last longer.
United States · Canada - recruitingPHASE2
Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD
This study is testing a new medicine, DCR-PHXC, for people with a rare kidney disease called Primary Hyperoxaluria Type 1 (PH1) who also have severe kidney problems. It aims to see how safe and effective the medicine is.
United States · France · Germany - recruitingNA
Rheopheresis as Adjuvant Treatment of Calciphylaxis
This study looks at a special blood filtering treatment called rheopheresis for people with a rare skin condition called calciphylaxis, often linked to kidney failure. It aims to see if this treatment, alongside usual care, can help heal painful skin ulcers better than usual care alone.
France - recruitingNA
An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL
This study looks at a new dialysis filter called Theranova to see if it makes people feel better, by removing more waste products. Patients will track their symptoms using a special app, LEVIL, over 28 weeks.
Canada - recruitingNA
Evaluation of the Level of Expression of CD45RC on T Lymphocytes as a Predictive Biomarker of Acute Rejection After Renal Transplantation
This study looks at a special marker on blood cells (CD45RC on T-cells) in kidney transplant patients. We want to see if having high levels of this marker before a transplant can predict if the new kidney will be rejected, helping us improve care.
France - recruiting
Association of Middle Molecules Clearance With HDF Volume
This study looks at a special type of dialysis called HDF. We want to understand if a higher volume of fluid used in HDF helps remove more 'middle molecules' from the blood, which could explain why some patients live longer.
United Kingdom - active not recruiting
Continuous Glucose Monitoring in People With Diabetes on Dialysis
This study looks at how blood sugar levels change in people with diabetes who are on dialysis, using a device called a continuous glucose monitor (CGM). It aims to see if these changes are linked to dialysis itself or to long-term health problems like hospital stays.
United Kingdom