- recruitingPHASE3
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
This study looks at a new treatment called benralizumab for people with severe asthma. It compares adding benralizumab to your usual asthma inhaler with just increasing the dose of your inhaler. We want to see if benralizumab helps control asthma better and is safe.
United States · Bulgaria · Canada - active not recruitingPHASE3
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma
This study is testing a new medicine, dexpramipexole, for people aged 12 and over with a specific type of asthma called eosinophilic asthma. It aims to see if the medicine can improve breathing, control asthma attacks, and boost quality of life.
United States · Argentina · Austria - ongoing, recruitingTherapeutic confirmatory (Phase III)
A randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, and tolerability of dexpramipexole administered orally for 24 weeks in participants with eosinophilic asthma (EXHALE-4)
This study is testing a new medicine, dexpramipexole, for adults with a type of asthma called eosinophilic asthma. We want to see if it helps improve breathing and asthma control over 24 weeks. Half the participants will get the new medicine, and half will get a dummy pill.
Romania · Poland - recruitingPHASE2
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
This study is testing a new medicine, KT-621, for adults with moderate to severe eosinophilic asthma. We want to see if it's safe, how well it works, and how it acts in the body.
United States · Germany · Poland