- recruiting
Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies
This study aims to understand why some children and young people with acute myeloid leukaemia (AML) don't get better or have their cancer come back. Researchers will collect blood and bone marrow samples to look closely at the cancer cells and test new ways to treat them, hoping to find better ways to fight this disease.
France - recruitingNA
Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program
This study aims to use a detailed genetic test called Whole Genome Sequencing (WGS) to help diagnose rare diseases and conditions caused by genetic changes. It's for people whose illness doesn't have a clear cause yet, or where a genetic link is suspected.
Germany - recruiting
Genetic Causes of Discrepant Clinic in Monogenic Twins
This study looks at identical twins where one twin has a rare, unexplained illness, and the other is healthy. Researchers use advanced genetic tests to find out if there's a genetic cause for the illness. The goal is to help diagnose and understand these conditions better.
Germany - active not recruiting
Genetic Determinants of Kidney Disease in People of African Ancestry With HIV
This study looks at why kidney problems are more common in people of African heritage living with HIV in the UK. It found that certain genes can increase this risk. The research aims to better understand these factors to improve care.
United Kingdom - enrolling by invitation
Prophylactic Prostatectomy for Prostate Cancer (PPPC)
This study is gathering opinions about a possible operation called a prophylactic prostatectomy. This operation might reduce prostate cancer risk in men with high genetic risk. We want to understand if men would consider this surgery and what their concerns would be.
United Kingdom - active not recruiting
The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer
The IMPACT study checks men with certain inherited gene changes (BRCA1, BRCA2, or Mismatch Repair genes) for prostate cancer. It also includes men without these changes. Researchers want to see if these gene changes increase prostate cancer risk and if screening helps.
United Kingdom