Geographic Atrophy research hub

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)

This study is looking into a new treatment called vonaprument for an eye condition called geographic atrophy (GA), which is a severe form of dry age-related macular degeneration (AMD). Researchers want to see if regular injections of vonaprument into the eye can help slow down or prevent vision loss.

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

This study looks at the long-term safety of a new eye treatment, JNJ-81201887, for geographic atrophy, a type of macular degeneration. It checks how people who received this treatment in earlier studies are doing over time.

A Study in Adults With Geographic Atrophy

This study is testing a new medicine, STL303, for Geographic Atrophy (GA), an eye condition that can cause blurry central vision. We want to see if it's safe and effective in slowing down this vision loss for people aged 60 and over.

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

This study is testing a new medicine, tinlarebant, for a serious eye condition called Geographic Atrophy (GA). Researchers want to see if it's safe and helps improve or slow down GA. It's a key step in finding new treatments.

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression

This study looks at how a specific type of age-related macular degeneration (AMD) progresses. It uses AI and eye scans to understand changes over two years, aiming to personalize future monitoring for people with this AMD.

Restoration of Central Vision With the PRIMA System in Patients With Atrophic AMD

This study is testing a new bionic vision system called PRIMA for people with a severe eye condition called geographic atrophy, a type of age-related macular degeneration (AMD). It aims to see if PRIMA can help people regain some central vision and if it's safe to use.

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

This study looks at how a serious eye condition called Geographic Atrophy (GA) develops over time. GA is a type of 'dry' Age-related Macular Degeneration (AMD). Researchers are checking for 'biomarkers' in blood and how they relate to changes in the eye.

Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

This early-stage study is looking at a new medicine called Pozelimab for an eye condition called Geographic Atrophy. It's the first time this medicine is being given to people, to understand if it's safe and how it works in the body.

A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

AN OPEN-LABEL EXTENSION (OLE) PHASE 3 TRIAL TO ASSESS THE SAFETY OF INTRAVITREAL ADMINISTRATION OF AVACINCAPTAD PEGOL (COMPLEMENT C5 INHIBITOR) IN PATIENTS WITH GEOGRAPHIC ATROPHY WHO PREVIOUSLY COMPLETED PHASE 3 STUDY ISEE2008 (GATHER2)