- recruitingHuman Pharmacology (Phase I)- First administration to humans
Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucoma
This study is looking at a new, tiny implant for people with glaucoma. It slowly releases medicine called timolol inside the eye to see how safe it is and if people can tolerate it well. This is an early-stage study to test it in humans for the first time.
Belgium · Germany - authorisedTherapeutic exploratory (Phase II)
Evaluation of the regenerative efficacy of Endoret® (PRGF-Plasm Rich in Growth Factors) on the ocular surface of glaucoma patients treated chronically with ocular hypotensive drugs, Evaluación de la eficacia regenerativa de Endoret® (PRGF-Plasma Rico en Factores de Crecimiento) en la superficie ocular de pacientes glaucomatosos tratados de forma crónica con fármacos hipotensores oculares
This study looks at a new treatment called Endoret® for people with glaucoma. It aims to see if this treatment can help improve the surface of the eye, especially for those who use eye drops long-term. We're checking how much it helps reduce eye dryness.
Spain - recruiting
Dresden Glaucoma and Treatment Study (DGTS)
This study looks at how well people with glaucoma are being cared for and treated at a special eye hospital. Researchers collect information from patient records to see what treatments work best over time, helping to improve care for everyone with glaucoma.
Germany - active not recruitingNA
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
This study is testing a new tiny implant called MINIject™ from iSTAR Medical. It aims to see how well it lowers eye pressure in people over 46 with a common type of glaucoma (primary open-angle glaucoma) and if it is safe to use. The goal is to help protect their vision.
United States · Canada · Switzerland - recruitingNA
Efficacy of Biofeedback Training for Glaucoma
This study looks into a special training called biofeedback for people with glaucoma. It aims to see if this training can help improve their eyesight and daily life by teaching their eyes to use clearer parts of their vision.
Canada - active not recruitingNA
Electrical Stimulation for the Treatment of Glaucoma
This study looks at whether a home electrical device can help treat open-angle glaucoma, a condition where eye nerves are damaged. We want to see if it's safe and effective over time.
United States · Germany - recruiting
Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
This study looks at a new eye scan called OCT to understand how glaucoma progresses over three years. Glaucoma damages the optic nerve, leading to vision loss. Researchers want to see how well this scan, alongside traditional tests, tracks changes in people with advanced glaucoma.
France - recruitingNA
A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma
This study is looking at a new small device called MINIject S+ for people with glaucoma. It aims to find the best way to put the device into the eye and see how well it works to lower eye pressure.
Honduras · United Kingdom - not yet recruiting
Retinal Ganglion Cell Neuroprotection Under Prostaglandin Analogues
This study looks at whether prostaglandin eye drops for glaucoma protect eyesight better than other drops, beyond just lowering eye pressure. Researchers are comparing patient records to see if these drops help retinal cells survive longer over three years.
Germany · Italy · Spain - authorisedTherapeutic use (Phase IV)
Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
This study looks at treating a type of eye pressure or glaucoma using a gentle laser or eye drops. We want to see if adding eye drops makes the laser treatment work faster and helps keep eye pressure down, aiming to prevent glaucoma from getting worse.
Finland - recruitingNA
World Sight Foundation Field Machine (WSFFM) Pilot
This study is testing a new eye machine called the World Sight Foundation Field Machine (WSFFM) for people with glaucoma. It aims to see how well it can spot serious vision loss, especially in places where advanced eye scanning equipment isn't available, to help doctors give earlier care.
United Kingdom