granulomatosis with polyangiitis and microscopic polyangiitis research hub

PREP-ANCA - Comparison of a strategy based on clinic-biological surveillance versus pre-emptive treatment with rituximab in the event of ANCA (anti-neutrophil cytoplasm antibodies) repositivation in patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)

This study compares two ways to manage two rare conditions: granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It looks at whether closely watching patients or giving them a treatment called rituximab early helps prevent their condition from flaring up again.