Heart Failure With Preserved Ejection Fraction research hub

Manganese-enhanced Magnetic Resonance Imaging (MEMRI) in Heart Failure With Preserved Ejection Fraction

This study looks at why people with a type of heart failure called HFpEF, especially those with Type 2 Diabetes, get so unwell. Using special MRI scans and dyes, researchers want to see how their hearts handle calcium and energy, comparing them to healthy volunteers.

The Effect of Obesity and Weight Loss in Heart Failure With Preserved Ejection Fraction

This study investigates if losing weight can help people with a specific type of heart failure called HFpEF. It aims to see if diet-led weight loss improves heart function, exercise ability, and quality of life in overweight or obese patients.

The Sarcopenia Study

This study looks at muscle weakness, called sarcopenia, in people with heart failure. Researchers want to see if different types of heart failure affect how common sarcopenia is, comparing heart failure patients to healthy people and those with type 2 diabetes.

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

This study looks at how a special low-calorie diet might help people with a type of heart failure where the heart struggles to relax properly. It aims to see if diet can improve heart function, symptoms, and exercise ability.

Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition

This study is looking at heart scarring, called fibrosis, in different heart muscle conditions. We're using a special scan with a new dye to better understand this scarring and how it changes over time. The aim is to find new ways to diagnose and treat these heart problems.

Biomarkers in Patients With Suspected HFpEF

This study looks for better ways to spot heart failure, especially in people with obesity or low levels of a common blood test. Researchers hope to find new blood markers to help doctors diagnose heart failure more accurately and earlier.

Effects of sodium-glucose cotransporter 2 inhibition on the mechanisms of heart failure with preserved ejection fraction

This study is looking at how a common heart failure medicine called Forxiga works in people who have a specific type of heart failure. It aims to understand the drug's effects on the heart's pumping ability and structure, helping us learn more about how it helps patients.

The effect of empagliflozin on peripheral microvascular dysfunction in heart failure with preserved ejection fraction

A Study to Learn How Different Amounts of the Study Medicine Called PF-07293893 are Tolerated and Act in the Body of Healthy Adults.

Impact of trimetazidine on endothelial function and biomarkers correlating with the prognosis of heart failure with preserved ejection fraction

J3E-MC-EZDB: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of LY3540378 in Adults with Worsening Chronic Heart Failure with Preserved Ejection Fraction (HFpEF)