Hematologic malignancies research hub
5 indexed studies · 2 currently recruiting
- ongoing, recruitingPhase I and Phase II (Integrated)- Other
A Phase 1/Phase 2 Clinical Study to Evaluate the Safety and Efficacy of a Combination of MK-4280 and Pembrolizumab (MK-3475) in Participants with Hematologic Malignancies
This study is looking at a new combination of treatments, including a medicine called Keytruda, for people with blood cancers. Doctors want to see how safe this new combination is and if it helps to treat these cancers. It's an early-stage study to learn more about the treatment.
Italy · Germany · Greece - active not recruitingPHASE1
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies
This study is looking into a new treatment called KQB198 for blood cancers in adults. Researchers want to see if KQB198 is safe and if it can help shrink tumours, either by itself or with another medicine. They are also trying to find the best dose.
United States · France · Germany - recruitingPHASE3
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
This study looks at the long-term safety and effectiveness of a cancer drug called pembrolizumab (and related treatments) for people with advanced cancers. It's for patients who are already receiving these treatments in other studies and want to continue.
United States · Argentina · Australia - recruitingPHASE2
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
This study is testing a new drug, nemtabrutinib, for people with certain blood cancers like lymphoma and leukaemia. It aims to see if the drug is safe and effective in treating these conditions.
United States · Argentina · Australia - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Study to Assess the Effect of Food on the Pharmacokinetics of CA-4948 in Healthy Male Subjects
This study is looking at how a new medicine, CA-4948, works in healthy men when they take it with different types of food. It's an early-stage study to understand how the body handles the medicine.
Netherlands