- recruitingNA
The Dragon PLC Trial (DRAGON-PLC)
This study looks at a new way to prepare people with certain liver cancers for surgery. It compares a standard procedure (PVE) with a new one (PVE + HVE) to see if more people can have life-saving surgery and live longer.
United States · Australia · Austria - recruitingPHASE1, PHASE2
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
This study is looking at a new medicine called Pumitamig, by itself or with another medicine called Ipilimumab. It's for people in the UK with advanced liver cancer that can't be removed by surgery. The main goal is to see how safe and well these treatments are tolerated.
United States · Australia · Chile - recruiting
A Simple Breath Test to Detect Liver Cancer and Monitor Liver Conditions
This study is testing a simple breath-test to find liver cancer earlier and check on other liver conditions. It looks for tiny chemicals in your breath. You could join if you have liver cancer, cirrhosis, or certain other liver issues, or tummy problems with a normal liver scan.
United Kingdom - authorisedTherapeutic exploratory (Phase II)
A Phase II, Multicenter, Open-Label Trial of DB-1311 in combination with BNT327 or DB-1305 in Participants with Advanced/Metastatic Solid Tumors
This study is testing new combinations of medicines (DB-1311 with BNT327 or DB-1305) for people with several types of advanced cancer. It aims to see how safe the treatments are and if they can shrink tumours, helping us find better ways to fight cancer.
Italy · Poland · France - not yet recruitingNA
International Study on Treatment of Liver (HCC) Patients With IRE
This study looks at a new treatment called irreversible electroporation (IRE) for people with a common type of liver cancer, hepatocellular carcinoma (HCC). It aims to collect information on how well the treatment works and how safe it is for patients with liver tumours.
United Kingdom - recruitingPHASE1
Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors
This study is testing a new drug, zanzalintinib, alone and with other medicines, for people with advanced cancers like kidney, prostate, and lung cancer. It's looking at safety and if the treatment shrinks tumours.
United States · Australia · Austria - active not recruitingPHASE1, PHASE2
A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours
This study is testing a new drug, HMBD-001, for advanced cancers where a protein called HER3 is active. We want to find the best dose, understand side effects, and see if it helps stop cancer growth, sometimes with another drug called enzalutamide.
United Kingdom