Hip and knee arthroplasties, Acute postoperative pain research hub

Safety of ibuprofen after major orthopaedic surgeries - the PERISAFE randomized clinical multicentre trial

This study looks at how safe ibuprofen is for people after hip or knee replacement surgery. We want to see if it causes serious problems like heart issues, blood clots, or stomach problems, compared to a dummy pill, to make sure patients get the best and safest pain relief.