- recruitingPHASE1
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
This study is testing a new drug, OKN4395, alone and with an existing cancer treatment, pembrolizumab, for various solid tumours. The main goals are to check its safety, how well it's tolerated, and if it helps fight cancer.
United States · Australia · United Kingdom - recruitingPHASE1, PHASE2
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
This study is looking at a new drug called MCLA-158 for advanced cancers like bowel and head and neck cancer. It aims to find the safest dose and see how well it works alone or with other treatments. It's for patients whose cancer has spread or come back.
United States · Belgium · France - recruitingPHASE1, PHASE2
Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma
This study is for people with a certain type of advanced head and neck cancer linked to HPV. It's testing a new 'vaccine-like' treatment called VB10.16 combined with an existing medicine, pembrolizumab, to see if it's safe and effective.
Czechia · France · Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to learn about the study medicine called PF-08046032 in people with advanced cancers.
This study is looking into a new medicine, PF-08046032, for people with advanced cancers like certain lymphomas and solid tumours. It's an early-stage study to understand how the medicine works and if it's safe for people aged 18 and over.
Spain