- ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Randomised, bioequivalence clinical trial of atorvastatin 80 mg capsules vs atorvastatin 80 mg film-coated tablets, after a single oral dose administration to healthy volunteers under fasting conditions in crossover replicated design.
This study is comparing two ways of taking atorvastatin 80 mg – a capsule versus a tablet. It's to see if they both deliver the same amount of medicine to your body. Healthy adult volunteers will take part.
Spain - recruitingPHASE3
Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days
This study compares two cholesterol-lowering medicines, obicetrapib and bempedoic acid, in adults with high cholesterol or mixed dyslipidemia. It looks at how well they reduce 'bad' cholesterol (LDL-C) and if they are safe, especially for people at higher risk of heart problems.
United Kingdom - active not recruitingPHASE3
Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes
This study looks at a new daily pill, enlicitide decanoate, for people at high risk of heart problems like heart attacks or strokes. It aims to see if this pill can help reduce these serious events safely, compared to a dummy pill.
United States · Argentina · Australia - recruitingPHASE1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
This study is testing a new medicine called CTX310 for people in the UK with high cholesterol and fats in their blood that haven't improved with usual treatments. It will check if the medicine is safe and how well people tolerate different doses. It's an early-stage study.
United States · Australia · New Zealand - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A clinical study of MK-3214 in healthy people (MK-3214-001)
This study is testing a new medicine, MK-3214, for people with high cholesterol. We want to see how safe it is and how it works in healthy men. It's an early-stage study to understand the medicine better.
Belgium