Cardiomyopathies research hub

The SMARTER Cardiomyopathy Study

This study looks into heart muscle diseases called cardiomyopathies. Researchers want to understand what causes them and why they affect people differently. They will collect blood samples and health information to learn more, hoping to find better ways to diagnose and treat these conditions.

Prospective Evaluation Of Exercise-Induced Cardiac Conduction Instability In Predicting Ventricular Fibrillation Events In Hypertrophic Cardiomyopathy

This study looks for a better way to identify people with a heart condition called hypertrophic cardiomyopathy (HCM) who are at risk of dangerous heart rhythms. It tests a new method involving an electrical vest and exercise against current approaches to see which is more accurate.

Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM)

This study looks at how adjusting pacemakers, particularly in people with thickened heart muscle (Hypertrophic Cardiomyopathy), can help the heart pump more easily. We’re studying if changing pacemaker settings can reduce symptoms like breathlessness and chest pain, and improve quality of life.

Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition

This study is looking at heart scarring, called fibrosis, in different heart muscle conditions. We're using a special scan with a new dye to better understand this scarring and how it changes over time. The aim is to find new ways to diagnose and treat these heart problems.

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

This study looks at new ways to understand hypertrophic cardiomyopathy (HCM), a heart condition, to better predict who might be at higher risk of serious problems like sudden cardiac arrest or heart failure. Researchers hope to find better tests to guide treatments.

A Long-term Safety Extension Study of Mavacamten (MYK-461) in Adults with Hypertrophic Cardiomyopathy Who Have Completed the MAVERICKHCM (MYK-461-006) or EXPLORER-HCM (MYK-461-005) Trials (MAVA-LTE)