- enrolling by invitation
Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank
This study is gathering information and samples from Canadians with inherited heart conditions that can cause sudden cardiac arrest. The goal is to better understand these conditions and improve ways to prevent sudden death across Canada.
Canada - recruiting
Multimodal Analysis of Endomyocardial Biopsies
Researchers are studying heart tissue from biopsies to understand different heart conditions better. This study aims to find unique signals in the tissue that could lead to improved diagnosis and treatment for diseases like cardiomyopathy and myocarditis.
Germany - recruiting
Retrospective Natural History Study of RASopathy-associated Cardiomyopathy (RAS-CM)
This study looks at past health records of children with a heart condition called RASopathy-associated cardiomyopathy (RAS-CM). We want to learn more about how this condition affects patients over time and gather information that could help develop new treatments for it in the future.
Germany - recruiting
HCMR Re-Imaging Study
This study aims to understand why some people with a heart condition called hypertrophic cardiomyopathy (HCM) develop serious heart problems. It's looking back at previous study participants to see if a substance found in their heart, called gadolinium, could help predict future heart issues.
United States · United Kingdom - recruiting
Multicentre Hypertrophic Cardiomyopathy Registry
This study is gathering health information from UK patients with Hypertrophic Cardiomyopathy (HCM) to better understand the condition. By collecting routine medical details from many hospitals, researchers hope to improve how HCM is diagnosed, treated, and how its future course is predicted.
United Kingdom - not yet recruiting
Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy
This study looks at why a heart medicine called mavacamten works differently for people with hypertrophic cardiomyopathy (HCM). We're trying to find out if your genes – both the one causing HCM and the one processing medicines – affect how well the treatment helps you.
United Kingdom - not yet recruiting
Mechanisms of Atrial Pathoelectrophysiology in HCM
This study looks into why an irregular heartbeat (atrial fibrillation) is common and hard to treat in people with a thickened heart muscle condition (HCM). Researchers will use heart scans and electrical tests to understand it better, hoping to find improved future treatments.
United Kingdom