Hypoxic ischemic encephalopathy research hub

SHINE trial - Effect of Sildenafil in association to Hypothermia on survival without brain lesions In term Neonates with hypoxic-ischemic Encephalopathy: a randomized, double-blinded, placebo-controlled, multicenter trial

This study looks at whether a medicine called sildenafil, given with cooling treatment, can help newborn babies who have had a lack of oxygen at birth. The aim is to see if it helps them survive without brain problems.