- ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase 1, open label, randomized, 2-sequence, 2-period, crossover, single center study to evaluate the pharmacokinetics of follitropin alfa from 2 manufacturing processes, administered as a single subcutaneous 450 IU dose to pituitary-suppressed healthy premenopausal female participants.
This study is looking at how a fertility medicine (follitropin alfa) is handled by the body. It compares two versions of the medicine in healthy women to understand how they work. This information helps us learn more about potential treatments for infertility.
Netherlands - ongoing, recruitingTherapeutic use (Phase IV)
The impact of the intensity of ovarian stimulation on embryo quality in predicted suboptimal responders. A randomized controlled trial.
This study looks at different ways to give fertility medicines to women who might find it harder to get pregnant. We want to see if changing the amount of medicine helps create better-quality embryos, which could improve chances of pregnancy.
Spain - authorisedTherapeutic use (Phase IV)
Intranasal nafarelin compared to subcutaneous triptorelin for triggering final oocyte maturation in ovarian stimulation: a non-inferiority randomised controlled clinical trial
This study compares two common fertility medications, Synarel nasal spray and daily Decapeptyl injections, to see which is better at helping eggs mature. It focuses on women undergoing fertility treatment for infertility, checking how many mature eggs are collected and looking at side effects and costs.
Spain - recruitingNA
Automation of Oocyte and Embryo Vitrification
This study compares a new automatic freezing method for eggs and embryos with the usual hand-freezing method. It aims to see if the new automated system works just as well. This could make fertility treatments more consistent and accessible for people hoping to start a family.
United Kingdom - authorisedTherapeutic use (Phase IV)
Luteal phase support following letrozole treatment in women undergoing intrauterine insemination: a multicenter randomized trial
This study looks at a vaginal progesterone medication (Cyclogest) after fertility treatment (letrozole and IUI) to see if it helps women get pregnant and have healthy babies. It's for women experiencing infertility.
Denmark - authorisedTherapeutic use (Phase IV)
Exogenous progesterone as ovulation trigger – a pilot study
This study is looking into using a medicine called progesterone to help eggs mature for women having fertility treatment. It wants to see if this method works well and how it affects hormone levels, as a different way to encourage egg development.
Portugal - ongoing, recruitingTherapeutic confirmatory (Phase III)
A randomized controlled trial comparing sequential of two shots of CFA vs CFA + rFSH for Elective Fertility Preservation. The 2-shot protocol.
Spain