- recruitingPhase III and phase IV (Integrated)
Efficacy of low dose amitriptyline vs. cognitive behavioural therapy for chronic insomnia and medical comorbidity: a randomized controlled non inferiority trial.
This study compares a low dose of a medicine called amitriptyline with talking therapy (CBT) for people with long-term sleep problems (insomnia) and other health issues. Researchers want to see if the medicine works just as well as the talking therapy.
Netherlands - recruitingTherapeutic exploratory (Phase II)
The CanISleepinMS Study: Effect of cannabidiol (CBD) on sleep quality in patients with multiple sclerosis, a series of 15 randomised, placebo-controlled N-of-1 trials
This study is looking into whether a cannabis-based oil (CBD) can help people with Multiple Sclerosis (MS) who have trouble sleeping. It's a small study where individuals try the CBD and a dummy oil to see which helps them sleep better.
Netherlands - recruitingNot Applicable
Assessment of the effect of transcranial direct current stimulation on insomnia in primary care patients
This study looks at a new way to help people with insomnia, a common sleep problem. It uses a gentle electrical current to the head with a device called Flow Neuroscience FL-100. Researchers want to see if this home-based treatment can improve sleep and offer a new option for those struggling to get a good night’s rest.
United Kingdom · England - recruitingNA
Health enSuite Insomnia: an App-based Treatment for Adult Chronic Insomnia
This study is testing a new app that helps adults with long-term sleep problems (insomnia). It uses a special programme called CBT-I to see if it can improve sleep and make it easier to get good rest without needing to see a therapist in person.
Canada - recruitingNA
Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-CBTi Study)
This study looks at a digital program to help healthcare workers, especially those on the front lines during COVID-19, sleep better. It checks if this online therapy can improve their sleep, mental health, and overall well-being.
Canada - recruiting
Mainz Register of Patients With Sleep Disorders
This study in Mainz, Germany, is looking at how different sleep disorders, like narcolepsy and insomnia, affect people's lives over time. It's collecting information about their symptoms, treatments, and how they feel about their quality of life to better understand these conditions.
Germany - recruiting
The IPAD Cohort Study: Insomnia and Positive Airway Pressure Adherence in Children and Adolescents
This study looks at how sleep problems like insomnia affect children and teenagers using a breathing machine (PAP) for sleep apnoea. Researchers want to understand if insomnia makes it harder to use the machine and if a child's background plays a role, hoping to improve future treatments.
Canada - recruitingNA
Online COgnitive Behavioural Therapy for Sleep and Mental Health for Older Adults With Insomnia and Subjective Cognitive Complaints
This study looks at an online program to help older adults with sleep problems and memory concerns. It teaches new ways to improve sleep and mental well-being, exploring if this online help can boost sleep, mood, and thinking skills.
Canada - not yet recruitingNA
Self-Help Booklets for Sleep in Adults With Pulmonary Hypertension
This study looks at whether special self-help booklets can improve sleep for adults in the UK who have a lung condition called pulmonary hypertension. These booklets are based on a proven sleep therapy and aim to help people sleep better and feel more rested.
United Kingdom - recruitingEARLY_PHASE1
Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
This study looks at how two common insomnia treatments, talking therapy (CBT-I) and a medication called trazodone, affect sleep and blood pressure. It aims to find out if these treatments work differently for people with different types of insomnia.
United States · Canada - recruitingNA
The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties
This study looks at an online course called 'The Sleep Course' for adults in Saskatchewan struggling with difficulties sleeping. It aims to see if this online therapy, which helps with sleep, depression, and anxiety, is effective and easy to use in real-world settings.
Canada - enrolling by invitation
Sleep Survey for Medical Trainees
This study is a survey for medical staff in training, like junior doctors, who work shifts or are on call. It wants to understand their sleep patterns, how much they know about sleep, and how sleep affects their work performance. It takes about 30-40 minutes to complete online.
United Kingdom - not yet recruitingNA
Examining a New Insomnia Treatment for People Living With Secondary Breast Cancer.
This study looks at a new way to help people with secondary breast cancer sleep better. It checks if a special programme, based on talking therapy, is helpful and easy to use. We want to see if it can improve sleep, energy, and overall well-being.
United Kingdom - recruitingNA
A Study Looking to Improve Sleep and Reduce Sedentary Behaviour in Those Living With Type 2 Diabetes Mellitus
This study aims to help people with Type 2 diabetes who struggle with sleep and are not very active. It explores how a special talking therapy and advice on being more active can improve sleep and overall health in this group.
United Kingdom - recruiting
Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®
This study looks at how QUVIVIQ, a medicine for insomnia, might affect pregnant women and their babies. We want to compare women who took QUVIVIQ during pregnancy with those who took other insomnia medicines or no medicine at all, to understand the outcomes for mothers and their newborns.
United States · Canada · France