Kidney Transplant Rejection research hub
6 indexed studies · 3 currently recruiting
- active not recruitingPHASE1, PHASE2
Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients
This study looks at a new treatment called TX200-TR101 for people getting a kidney transplant from a living donor. It aims to help the body accept the new kidney and prevent it from being rejected. Researchers want to check if it's safe and how well it works.
Belgium · Netherlands · United Kingdom - recruiting
Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients
This study is testing a new blood test for kidney transplant patients. It aims to find hidden antibodies that can damage the new kidney. Researchers also want to see if older patients are better protected against rejection and if we can predict who will develop these antibodies.
United Kingdom - recruitingPHASE2, PHASE3
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
This study is looking at a new medicine called frexalimab for adults having a kidney transplant. It compares frexalimab to a standard medicine, tacrolimus, to see if it's safe and works well to prevent the body rejecting the new kidney.
Australia · Chile · China - active not recruitingNA
Clinical Impact of the IBox As an Early Intervention TooL
This study is looking at a new way to check on people who have had a kidney transplant. It’s called Predigraft. The aim is to see if using Predigraft can help doctors spot problems with the new kidney earlier, potentially leading to better long-term health for patients.
Austria · France · Germany - enrolling by invitationPHASE2
Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients
This study looks at the long-term safety and effectiveness of a new drug, tegoprubart (also called AT-1501), compared to a standard drug, tacrolimus. It's for people who have had a kidney transplant to help prevent their body from rejecting the new kidney.
United States · Australia · Brazil - active not recruiting
Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)
This study is checking on people who had a special treatment (TX200-TR101) for kidney transplant rejection up to 15 years ago. Researchers want to see how everyone is doing long-term to make sure the treatment is safe and well-tolerated.
Belgium · Netherlands · United Kingdom