Kidney Transplant Rejection research hub
10 indexed studies · 5 currently recruiting
- recruitingPHASE2, PHASE3
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
This study is looking at a new medicine called frexalimab for adults having a kidney transplant. It compares frexalimab to a standard medicine, tacrolimus, to see if it's safe and works well to prevent the body rejecting the new kidney.
United States · Argentina · Australia - recruiting
Trifecta-Kidney cfDNA-MMDx Study
This study looks at new ways to check for rejection in kidney transplant patients. It compares a new blood test (DD-cfDNA) with a special biopsy test (MMDx) and traditional checks to see which is best at finding rejection accurately.
United States · Australia · Canada - recruiting
Impact of the Microbiota on the Likelihood of Renal Graft Rejection
This study looks at gut and blood germs in kidney transplant patients. We want to see if certain germs are linked to the body rejecting the new kidney, especially in patients using a specific anti-rejection medicine called Nulojix during their first year after transplant.
France - active not recruiting
PROACT Pilot Trial
This study looks at a new urine test called CXCL10 to help spot kidney rejection earlier in children who have had a kidney transplant. Early detection means doctors can treat rejection sooner, potentially saving the kidney and improving the child's health after transplant.
Canada - active not recruitingPHASE1, PHASE2
Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients
This study looks at a new treatment called TX200-TR101 for people getting a kidney transplant from a living donor. It aims to help the body accept the new kidney and prevent it from being rejected. Researchers want to check if it's safe and how well it works.
Belgium · Netherlands · United Kingdom - active not recruitingNA
The smartNTx Trial:Telemedical Management Versus Standard Aftercare in Kidney Transplant Recipients (KTR)
This study compares standard care after a kidney transplant with extra support through a smartphone app. It aims to see if using the app, which helps track health and communicate with doctors, can improve long-term transplant success, wellbeing, and reduce complications for patients in Germany.
Germany - recruiting
Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients
This study is testing a new blood test for kidney transplant patients. It aims to find hidden antibodies that can damage the new kidney. Researchers also want to see if older patients are better protected against rejection and if we can predict who will develop these antibodies.
United Kingdom - active not recruitingNA
Clinical Impact of the IBox As an Early Intervention TooL
This study is looking at a new way to check on people who have had a kidney transplant. It’s called Predigraft. The aim is to see if using Predigraft can help doctors spot problems with the new kidney earlier, potentially leading to better long-term health for patients.
Austria · France · Germany - enrolling by invitationPHASE2
Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients
This study looks at the long-term safety and effectiveness of a new drug, tegoprubart (also called AT-1501), compared to a standard drug, tacrolimus. It's for people who have had a kidney transplant to help prevent their body from rejecting the new kidney.
United States · Australia · Brazil - active not recruiting
Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)
This study is checking on people who had a special treatment (TX200-TR101) for kidney transplant rejection up to 15 years ago. Researchers want to see how everyone is doing long-term to make sure the treatment is safe and well-tolerated.
Belgium · Netherlands · United Kingdom