- active not recruiting
Study in Patients With Decompensated Liver Cirrhosis
This study looks at people with liver scarring (cirrhosis) who have recently had a serious liver problem. We want to understand how their illness progresses over time, using information from their regular doctor visits, to help develop better future treatments.
Spain · United Kingdom - recruitingPHASE3
A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis
The PROMISE trial is testing a new capsule treatment for people with liver scarring (cirrhosis), particularly those whose condition is linked to alcohol or fatty liver disease. These capsules contain healthy gut bacteria from donors and aim to reduce serious infections.
United Kingdom - recruitingNA
Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC
This study looks at a new test called Elecsys® GAAD to help doctors find liver cancer (hepatocellular carcinoma) earlier in people with liver scarring (cirrhosis). The aim is to see if this new test can improve current screening methods and help patients get treatment sooner.
United Kingdom - recruitingPHASE2
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
This study is looking at a new combination treatment for people with severe liver disease (cirrhosis) who have recently been in hospital. We want to see if combining two existing medicines, albumin and enoxaparin, is safe and helps improve outcomes after leaving the hospital.
France · Germany · Italy - recruiting
Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis
This study looks for new ways to predict how well people with severe liver cirrhosis will recover after a hospital stay. Researchers are using body markers to better understand the disease and help doctors give more personalised care to improve patient outcomes.
France · Germany · Italy - active not recruiting
naVIGation Invitations Liver surveillANce upTake
This study looks at new ways to help people attend vital liver scans for conditions like liver scarring or hepatitis B. It explores if special invitations and support from a Patient Navigator can improve attendance and lead to earlier cancer detection.
United Kingdom - recruiting
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
This study looks at how well people with severe liver disease (ACLF) do after a liver transplant compared to those with less severe liver disease. It also checks why some people with ACLF don't get a transplant and how they fare.
United States · Argentina · Australia - recruiting
A Simple Breath Test to Detect Liver Cancer and Monitor Liver Conditions
This study is testing a simple breath-test to find liver cancer earlier and check on other liver conditions. It looks for tiny chemicals in your breath. You could join if you have liver cancer, cirrhosis, or certain other liver issues, or tummy problems with a normal liver scan.
United Kingdom - authorisedHuman Pharmacology (Phase I)- First administration to humans
A study to evaluate the safety and tolerability of single ascending doses of AGMB-101 in healthy participants (Part A) and patients with liver cirrhosis (Part B).
This study is looking at a new medicine called AGMB-101. It wants to see how safe it is and how well people tolerate it. First, healthy volunteers will try different doses. Then, people with a liver problem called cirrhosis will also try it. This is an early stage of testing new medicines.
Belgium