- active not recruitingNA
The Costs and Effectiveness of Cognitive Functional Therapy for People with Persistent Low Back Pain in Coventry.
This study looks at a special type of therapy called Cognitive Functional Therapy (CFT) for long-term back pain in Coventry. It wants to see if CFT helps people who also face health inequalities or have other health problems, checking how well it works and its costs.
United Kingdom - authorisedTherapeutic confirmatory (Phase III)
A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo and Active-Controlled Phase III Therapeutic Superiority Trial Comparing the Efficacy and Tolerability of a Fixed-Dose Combination of Diclofenac potassium + Thiocolchicoside to Diclofenac potassium (Cataflam®) in Patients with Acute Severe Low Back Pain.
This study is looking at a new combination of two common pain medications, diclofenac potassium and thiocolchicoside, to see if it's better than diclofenac alone for severe back pain. Researchers are also checking for side effects.
Cyprus · Greece - active not recruiting
Personalisation of Prosthetic Care for Lower- Limb Amputees
This study looks at why some people with a lower-leg amputation get back pain. Researchers want to understand how walking styles, muscle use, and feelings like depression affect back pain. The aim is to help create better care plans for amputees.
United Kingdom - authorisedTherapeutic confirmatory (Phase III)
ZAMBA: Zoledronic Acid for Modic Back Pain. A randomized, double blind, placebo-controlled, multicenter trial
This study, called ZAMBA, is looking at whether a medicine called zoledronic acid can help people with ongoing back pain. It compares this medicine to a dummy treatment (placebo) to see if it improves daily activities and pain levels over one year.
Norway - ongoing, recruitingTherapeutic exploratory (Phase II)
Intervertebral Disc REgeneration mediated by Autologous Mesenchymal stem/stromal cells intradiscal injection: a phase IIB randomized clinical trial
This study looks into a new way to treat ongoing lower back pain. It uses a patient's own stem cells injected into the back discs to see if it lessens pain and improves daily function over 12 months.
Italy - recruitingNA
Motivating Core-muscle Exercises With Wearable Sensors, Haptics and Interactive Gaming
This study looks at a special smartbelt and app for people with long-term back pain. It checks if using this system during exercise helps reduce pain and improve daily life more than usual care alone.
United Kingdom