- ongoing, recruitingTherapeutic use (Phase IV)
An investigation of clinical outcomes and inflammatory response to heparin free extracorporeal membrane oxygenation support during clinical lung transplantation – a prospective double-blind randomised feasibility study. “Zero-Hep”
This study, called "Zero-Hep," is looking into how well a new way of doing lung transplants works. It's focused on a special type of life support called ECMO, but without using a blood-thinning medicine called heparin. Researchers want to see if this method causes fewer blood clots and other problems.
Austria - recruitingNA
Quantiferon CMV to Identify Treatment Need for Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT)
This study looks at a blood test for organ transplant patients with Cytomegalovirus (CMV) infection. It aims to see if this test can help doctors decide who really needs antiviral medicine, to avoid unnecessary treatment and its side effects.
France - recruiting
Trifecta-Lung cfDNA-MMDx Study
This study aims to find better ways to check for organ rejection after a lung transplant. It's comparing a new blood test (dd-cfDNA) with a special biopsy test (MMDx) to see how well they work together. The goal is to make checking for rejection more accurate and safer.
United States · Australia · Austria - authorisedTherapeutic confirmatory (Phase III)
REVOLUTION; Randomized controlled trial comparing immediate versus extended release tacrolimus; reducing calcineurin inhibitor related toxicity in lung transplantation patients
This study looks at two different ways to give a medicine called tacrolimus to people who have had a lung transplant. The aim is to see if one way causes fewer side effects, especially problems with kidneys. It compares a standard capsule with a longer-acting tablet.
Netherlands