Lupus Erythematosus, Systemic research hub
5 indexed studies · 3 currently recruiting
- recruitingPHASE2
A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
This study is testing a new cell therapy called CC-97540 for people with lupus and lupus kidney disease. It aims to see if it's safe and effective when other treatments haven't worked well enough.
United States · Argentina · Austria - active not recruitingPHASE3
A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
This study is testing a new injection, litifilimab, for adults with active lupus (SLE) who are already on standard treatments. Researchers want to see if it improves lupus symptoms and is safe over 52 weeks.
United States · Argentina · Belgium - recruitingPHASE3
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
This study is looking at a new medicine called nipocalimab for adults with moderate to severe lupus. It compares nipocalimab to a dummy treatment (placebo) to see if it can help reduce inflammation and improve lupus symptoms.
United States · Argentina · Brazil - recruitingPHASE2
A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)
This study is testing a new cell therapy called rapcabtagene autoleucel for severe lupus (SLE) or lupus affecting the kidneys (lupus nephritis). It aims to see how well it works and if it's safe for people whose current treatments aren't effective.
United States · Australia · Austria - active not recruitingPHASE3
A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus
This study is testing a new medicine, cenerimod, for people with a type of lupus called Systemic Lupus Erythematosus (SLE). It aims to see if adding cenerimod to current treatments helps reduce symptoms and is safe.
United States · Chile · Czechia