- ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
This study is testing a new medicine, Ultomiris, for adults with kidney diseases called Lupus Nephritis or IgA Nephropathy. Doctors want to see if it reduces protein in their urine and helps their kidneys work better, compared to a dummy medicine.
Italy · Poland · Spain - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Randomized, Double‑blind, Placebo‑controlled, Dose‑finding Study to Evaluate the Efficacy and Safety of ALXN2050 in Adult Participants with Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
This study is testing a new medicine, ALXN2050, for adults with kidney diseases called lupus nephritis or IgA nephropathy. Researchers want to see if the medicine can reduce protein in the urine and if it's safe.
Germany · Spain · Italy - recruitingPHASE1
Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis
This study is testing new medicines, Vonsetamig and Odronextamab, for adults with a kidney condition called Lupus Nephritis. It aims to find out if these medicines are safe and how the body reacts to them over time. The study wants to understand potential side effects and how much of the drug stays in the blood.
United States · Germany · South Korea